Usage In the pediatric population (age 18 years or younger), CT imaging of the head is thought to be associated with an increased risk of lethal malignancy over the life of the patient, with the risk decreasing with age. The estimated risk of lethal malignancy from a head CT in one year is 1 in 1000-1500. The risk decreases to 1 in 5000 once the patient is 10 years old. The Pediatric Emergency Care Applied Research Network (PECARN) conducted the largest study to derive and validate clinical prediction rules to identify children with very low risk of Clinically Important Traumatic Brain Injury (ciTBI) following blunt head trauma who do not need imaging. As a result, the PECARN Pediatric Head Injury Prediction Rule can assist providers in determining which pediatric patients they can safely discharge without obtaining a head CT. Of note, the PECARN study results suggest overall TBI in children is rare with low rates of TBI on head CT (5.2%) and even lower rates of ciTBI (0.9%).
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Summary The PECARN Pediatric Head Injury Prediction Rule is a well-validated clinical decision aid. The criteria allow clinicians to safely rule out the presence of clinically important traumatic brain injuries among pediatric head injury patients without the need for CT imaging.
| Recommendations | Criteria | PECARN Study Findings |
CT not recommended (< 2 years old) | - < 2 years
- "No" to the following: GCS¹ ≤ 14 or other signs of AMS² or palpable skull fracture
- "No" to the following: Occipital, parietal or temporal scalp hematoma; history of LOC³ ≥ 5 sec; not acting normally per parent or severe mechanism⁴ of injury
| - Represents 53.2% of population.
- Risk of ciTBI⁷ (<0.02%) which is exceedingly low, generally lower than risk of CT-induced malignancies.
|
CT not recommended ( ≥ 2 years old) | - ≥ 2 years
- "No" to the following: GCS ≤ 14 or other signs of AMS or signs of basilar skull fracture
- "No" to the following: History of LOC or history of vomiting or severe headache or severe mechanism of injury
| - Represents 57.2% of population.
- Risk of ciTBI (<0.05%) which is exceedingly low, generally lower than risk of CT-induced malignancies.
|
CT recommended (< 2 years old) | - < 2 years
- "Yes" to the following: GCS ≤ 14 or other signs of AMS or palpable skull fracture
| - Represents 13.9% of population.
- Risk of ciTBI (4.4%)
|
CT recommended (≥ 2 years old) | - ≥ 2 years
- "Yes" to the following: GCS ≤ 14 or other signs of AMS or signs of basilar skull fracture
| - Represents 14% of population.
- Risk of ciTBI (4.3%)
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| Observation versus CT on the basis of other clinical factors⁵ (< 2 years old) | - < 2 years
- "Yes" to the following: GCS ≤ 14 or other signs of AMS or palpable skull fracture
- "Yes" to the following: Occipital, parietal or temporal scalp hematoma; history of LOC ≥ 5 sec; not acting normally per parent or severe mechanism of injury
| - Represents 32.9% of population.
- Risk of ciTBI (0.9%)
- Patients with certain isolated findings (i.e. with no other findings suggestive of traumatic brain injury) have a risk of ciTBI substantially lower than 1%
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| Observation versus CT on the basis of other clinical factors (≥2 years old) | - ≥ 2 years
- "Yes" to the following: GCS ≤ 14 or other signs of AMS or signs of basilar skull fracture
- "Yes" to the following: History of LOC or history of vomiting or severe headache or severe mechanism of injury
| - Represents 28.8% of population.
- Risk of ciTBI (0.8%)
- Patients with certain isolated findings (i.e. with no other findings suggestive of traumatic brain injury) have a risk of ciTBI substantially lower than 1%
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¹Glascow Coma Scale (GCS)
²Other signs of altered mental status (AMS): Agitation, somnolence, repetitive questioning, or slow response to verbal communication.
³Loss of Consciousness (LOC)
⁴Severe mechanism:
- Motor vehicle crash (MVC) with patient ejection
- MVC with death of another passenger or rollover
- Pedestrian or bicyclist w/o helmet struck by motorized vehicle
- Fall from > 3 ft (0.9 m)
- Head struck by high-impact object
⁵Other clinical factors include:
- Clinician experience
- Multiple versus isolated findings⁶
- Worsening symptoms or signs after emergency department observation
- Age < 3 months
- Parental preference
⁶Isolated findings:
- Isolated Loss of Consciousness
- Isolated headache
- Isolated vomiting
- Certain types of isolated scalp hematomas in infants > 3 months
⁷Definition of clinically important traumatic brain injury (ciTBI)
(any of the following)
- Death from traumatic brain injury (TBI)
- Neurosurgical intervention for TBI
- Intubation of more than 24 hours for TBI
- Hospital Admission of 2 nights or more for the TBI in association with TBI on CT^
^Definition of TBI on CT (any of the following):
- Intracranial hemorrhage or contusion
- Cerebral edema
- Traumatic infarction
- Diffuse axonal injury
- Shearing injury
- Sigmoid sinus thrombosis
- Midline shift of intracranial contents or signs of brain herniation
- Diastasis of the skull
- Pneumocephalus
- Skull fracture depressed by at least the width of the table of the skull
Management Considerations:
- Clinical judgement also plays a key role in work-up and disposition. For example, judgement may be based on:
- If the event was witnessed or historical reliability
- Patient age
- Parental preference
- Clinical deterioration
- Patient co-morbidities
- For those with suspected or radiologically-confirmed traumatic brain injury (TBI):
- First assess ABC's and consider neurosurgical/ICU consultation
- Consult institutional protocols on, for example:
- Fluid management
- Seizure prophylaxis
- Hypertonic saline or mannitol
- Admission or disposition
- For those not imaged, observation for 4-6 hours to monitor changes in clinical status.
- For those discharged
- Reassurance, education and strict return precautions.
- Follow-up with primary care or neurologist.
- If concussion suspected, return to play or school anticipatory guidance.
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