Summary
The ATRIA Bleeding Risk Score considers major and minor risk of hemorrhage and bleeding in patients prior to beginning warfarin therapy.The ATRIA study included patients with non-valvular, non-transient atrial fibrillation.Major hemorrhage was defined as fatal, requiring transfusion of ≥2 units pRBCs, or hemorrhage into critical anatomic site (intracranial, retroperitoneal, etc.) Criteria Risk FactorPoint ValueAnemia3Severe Renal Disease/Dialysis3Age ≥75 2Prior Hemorrhage1Hypertension 1 Results Risk LevelPointsAnnual Risk of HemorrhageRecommendationLow Risk<40.76%Reasonable to start warfarin therapIntermediate Risk42.6%Alternatives to warfarin therapy can be consideredHigh Risk>45.8%Alternatives to warfarin therapy ought to be strongly considered